Female Sex Hormones and Cognitive AgingPrincipal Investigator
Dr. Barry Setlow
Department
Psychiatry
My research project investigates the impact of female sex hormones on cognition, specifically analyzing how prefrontal cortex-mediated cognition alters with age, and the difference between sexes
BACKGROUND
RELEVANT SOURCES
Age-Related Declines in Prefrontal Cortical Expression of Metabotropic Glutamate Receptors that Support Working Memory, Hernandez et al. 2018
Decline of prefrontal cortical-mediated executive functions but attenuated delay discounting in aged Fischer 344 brown Norway hybrid rats, Hernandez et al. 2017
Deconstructing value-based decision making via temporally selective manipulation of neural activity: Insights from rodent models, Orsini et al. 2019
Distinct manifestations of executive dysfunction in aged rats, Beas et al. 2013
GABAB receptors in prelimbic cortex and basolateral amygdala differentially influence intertemporal decision making and decline with age, Hernandez et al. 2022
Optogenetic dissection of basolateral amygdala contributions to intertemporal choice in young and aged rats, Hernandez et al. 2019
Prefrontal Cortical GABAergic Dysfunction Contributes to Age-Related Working Memory Impairment, Banuelos et al. 2014
Testicular hormones mediate robust sex differences in impulsive choice in rats, Hernandez et al. 2020